In addition, at different concentrations, triptolide was located to induce the phosphorylation of p53 on the serine-fifteen residue in HepG2 cells. Activating the tumor suppressor gene p53 can induce the apoptosis of liver most cancers cells 36. The pentacyclic triterpenoid celastrol is determined as a major bioactive metabolite of T. https://triptolide-effectiveness81357.sharebyblog.com/31328444/little-known-facts-about-triptolide