Background & aim: Acute rheumatic fever is an autoimmune disease that mainly affects the large joints. Early treatment of a throat infection following group A streptococcus prevents of acute rheumatic fever. Given the low prevalence of the disease. especially in a situation where there is excessive use of antibiotics in Iran. https://www.ealisboa.com/great-deal-Pentair-Union-Collar-2-U11-200PS-super-offer/